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Forward2025 Clinician Corner - Histologic changes of basal cell carcinomas during vismodegib treatment
We report a case of a 63-year-old man with a history of numerous basal cell carcinomas (BCCs) on vismodegib who developed a pink subcutaneous nodule that was thought to be either a BCC or an epidermal inclusion cyst. Sections displayed a dome-shaped lesion composed of large dermal nodules of epithelioid cells with variable cytology. Some of the dermal nodules demonstrated squamatization of the epithelioid cells while others had a predominantly basaloid phenotype. Central necrosis was present in the majority of the large dermal nodules, but the lesion did not stain with CK7 or CK20, helping to rule out internal metastases. The epithelial nodules stained strongly with pancytokeratin (AE1/AE3), p40, and stained lightly with BCL-2, supporting the diagnosis of BCC. However, Ber-EP4 being negative and the presence of significant squamatization suggest vismodegib can alter both the histological and immunophenotype of BCCs. This phenomenon has rarely been reported in literature.
Maternity Tour: Irving (In-Person Patient Tour)
Our In-Person Maternity Tour offers expectant families the chance to get familiar with the Labor & Delivery and New Family Center units. This guided tour helps ease any uncertainty by showing you what to expect and where to go when the big day arrives.
Following the tour, we’ll provide:
• Pre-registration assistance
• Practical information and resources for new parents
• An opportunity to ask questions and feel more prepared
This is a great way to feel confident and comfortable before your baby’s arrival!
Dads Class - Fort Worth (In-Person Patient Class)
Calling Dads: Ready to level up your parenting game?
This Dad taught class will equip you with the tools and knowledge to navigate the exciting, sometimes unpredictable journey of pregnancy and parenting.
You will learn how to support your partner through pregnancy and birth. Learn survival tips for those sleep deprived months with a newborn and how to master the art of diaper duty.
Join us for some laughs, learning and whole lot of support as you prepare to welcome your little bundle of joy. Let's get ready for fatherhood!
Category
- Pediatric Care
Format
- In-Person
Credits
Cost $0.00
Tour de Maternidad: Irving - Espanol (Tour presencal para pacientes)
Nuestro recorrido presencial de maternidad ofrece a las familias en espera la oportunidad de familiarizarse con las unidades de Trabajo de Parto y Centro de Nuevas Familias. Esta visita guiada ayuda a aliviar cualquier incertidumbre al mostrarles qué esperar y a dónde ir cuando llegue el gran día.
Después del recorrido, proporcionaremos:
• Asistencia con la preinscripción
• Información práctica y recursos para nuevos padres
• Una oportunidad para hacer preguntas y sentirse más preparados
¡Esta es una excelente manera de sentirse seguros y cómodos antes de la llegada de su bebé!
Infant CPR & Safety: Irving (In-Person Patient Class)
This non-certification class is designed specifically for parents, grandparents, and caregivers of infants and children. Through essential hands-on practice, you’ll build the skills and confidence needed to respond effectively to life-threatening situations.
In this class, you’ll learn:
• Basic lifesaving techniques tailored for infants and children
• How to recognize and respond to emergencies
• Ways to reduce the risk of preventable accidents at home and beyond
This practical, supportive class will leave you feeling more prepared to protect the little ones in your care.
Breastfeeding Online Class: Dallas (Online Patient Course)
Learn about breastfeeding from the comfort of your home. Not every family is able to attend parent education classes in person, while others learn better with a self-study class. This interactive, web-based instruction contains animated illustrations, videos and games to make learning easy and fun.
An Invitation to the online course will be given to you within 5 business days after you have completed the registration process.
Maternity Tour: Dallas - In Person (In-Person Patient Tour)
This interactive tour provides the expectant couple an opportunity to become familiar with labor & delivery, as well as the Postpartum and Nursery Units. All questions are welcomed.
NOTE:
Pre-registration is required. These tours are very popular and have limited space, do NOT enroll in more than one tour. Childbirth classes include a tour, you do not need to enroll in a standalone tour separately.
Category
- Women's Health
Format
- In-Person
Credits
Cost $0.00
Wired for Life - Dallas - In-Person (In-Person Patient Class)
The Dallas electrophysiology department team provides you with the education, guidance, and encouragement you need to live a healthy life with your implantable cardioverter defibrillator (ICD). Learn from registered nurses and others about living with an ICD through a class specifically designed for you and your loved ones.
Category
- Heart and Vascular
Format
- In-Person
Credits
Cost $0.00
Hospital Tour: College Station (In-Person Maternity Tour)
Our hospital tour offers expectant parents and siblings a chance to prepare for the big day by becoming familiar with the birth environment. You'll get a guided look at our facilities, and we'll answer any questions to help ease anxiety and make the experience more comfortable and enjoyable.
This tour is offered at no cost and is a great way to feel more confident and ready for your hospital stay.
Please note: Tours are also included as part of the childbirth preparation class.
Breastfeeding Class: College Station (In-Person Patient Class)
This class is designed for expectant parents and focuses on both the joys and common concerns of breastfeeding. You'll learn about the benefits for both mother and baby, how to initiate feedings, maintain a healthy milk supply, and navigate common challenges.
Topics also include:
• Combining breastfeeding with returning to work
• Expressing and safely storing breast milk
• Practical tips for a successful breastfeeding experience
Whether you're planning to breastfeed or just exploring your options, this class offers supportive, evidence-based guidance to help you feel confident and prepared.