2025 Clinician Corner - Biodegradable temporizing matrix utilization on a pediatric burn following an exploratory laparotomy

Overview

Abstract 

Biodegradable temporizing matrix (BTM) is a synthetic polymer used to promote new tissue growth in full-thickness wounds by providing a framework for additional tissue coverage of a new fascial closure, demonstrating its potential for use in recent incision closure and wound healing. While a case study on a pediatric patient with deep soft tissue friction burns exists, there are no reports on BTM utilization immediately following the closure of a surgical excision. This case report describes the successful use of BTM in promoting wound healing and skin graft incorporation in a 19-month-old female patient with severe scalding burns and a recent exploratory laparotomy. Following an excision of the burn wounds and closure of the surgical incision, BTM was secured over the incision site, and a split-thickness skin graft was applied using the RECELL system. Despite the initially limited blood flow around the incision, the BTM facilitated additional tissue coverage of a new fascial abdominal closure and vascularization, thus enabling successful graft incorporation and incision healing. This case highlights the untapped potential of BTM in supporting wound healing and skin grafting over recently closed incisions, expanding its application beyond traditional use in full-thickness wounds.

Keywords:  Biodegradable temporizing matrix; burns; full-thickness wounds; incision healing; pediatric; skin grafting

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Faculty credentials/disclosure 

The planners and faculty for this activity have no relevant financial relationships to disclose. The patient consented to the publication of this report.

Process

Click the "add to cart/begin" button, pay any relevant fee, take the quiz, complete the evaluation, and claim your CME credit.  You must achieve 100% on the quiz with unlimited attempts available.

  • By completing this process, you are attesting that you have read the journal article.

Expiration date:

Credit eligibility for this article is set to expire on July 1, 2026.

Learning Objectives

After completing the article, the learner should be able to:

  • Describe how biodegradable temporizing matrix (BTM) facilitates wound healing and graft incorporation through mechanisms such as vascularization, tissue regeneration, and providing a scaffold for granulation tissue, especially in freshly closed surgical incisions.
  • Recognize the importance of multidisciplinary care for pediatric burn patients, including addressing burn-related complications (e.g., gastric ulceration, abdominal compartment syndrome), and the criteria for BTM application in cases involving severe burns and surgical incisions.

Key Points 

  • Osteonecrosis has been associated with HIV/AIDS; therefore, it is an important differential to be considered in people with HIV presenting with pathological fracture.  
  • Elimination of active dental and periodontal disease should be considered in people with HIV, as the jaw is more prone to osteonecrosis, with a high remodeling rate. 

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Course summary
Available credit: 
  • 1.00 American Board of Internal Medicine (ABIM) MOC Part 2
    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
  • 1.00 American Board of Surgery (ABS) Accredited CME
    Successful completion of this CME activity enables the learner to earn credit toward the CME requirement of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.
  • 1.00 AMA PRA Category 1 Credit™
    The A. Webb Roberts Center for Continuing Medical Education of Baylor Scott & White Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
  • 1.00 Attendance
Course opens: 
07/01/2025
Course expires: 
07/01/2026
Cost:
$25.00

Faculty

  • Namratha Mohan, MBA - School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
  • Shruti Patel, MBA - School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
  • Genesy Aickareth, BS - School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
  • John A. Griswold, MD - Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
  • Alan Pang, MD - Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA

Accreditation

Accreditation

The A. Webb Roberts Center for Continuing Medical Education of Baylor Scott & White Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation

AMA PRA Category 1 Credit™

The A. Webb Roberts Center for Continuing Medical Education of Baylor Scott & White Health designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ABS CC

Successful completion of this CME activity enables the learner to earn credit toward the CME requirement of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.

ABIM MOC

 Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

 

Available Credit

  • 1.00 American Board of Internal Medicine (ABIM) MOC Part 2
    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
  • 1.00 American Board of Surgery (ABS) Accredited CME
    Successful completion of this CME activity enables the learner to earn credit toward the CME requirement of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.
  • 1.00 AMA PRA Category 1 Credit™
    The A. Webb Roberts Center for Continuing Medical Education of Baylor Scott & White Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
  • 1.00 Attendance

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Price

Cost:
$25.00
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