2025 Monkeypox: Another Pandemic in the Making
ABSTRACT
Monkeypox is a zoonotic disease caused by the monkeypox virus, which is a member of the Poxviridae family of viruses. It is transmitted through direct or indirect contact with fluid secretions. Initial symptoms include fever, chills, headache, and malaise, followed by a maculopapular rash that starts on the face and progresses centrifugally. Polymerase chain reaction is the preferred laboratory test for the diagnosis, and management is mostly supportive. The clinical presentation of monkeypox is quite similar to that of another member of the Poxviridae family: smallpox, which wreaked havoc in the 20th century, before being eradicated with the help of the vaccinia virus vaccine in 1977. This vaccine protects not only against smallpox but also monkeypox; therefore, when use of this vaccine was discontinued, monkeypox had a new susceptible population to infect and way to proliferate and evolve. Initially the disease spread in Africa, but now the more evolved monkeypox is quickly spreading to other countries. On July 23, 2022, the World Health Organization declared this multicountry outbreak a public health emergency of international concern. Given its mutating ability and high transmissibility, we need to quickly devise measures to control this virus before it turns into a pandemic.
Faculty credentials/disclosure
Prinay Sohal and Aakanksha Gupta are final-year MBBS students at Dayanand Medical College and Hospital, Ludhiana, India. Shefali Gupta, MBBS, MD, is assistant professor in microbiology, All India Institute of Medical Sciences, AIIMS Raebareli, Uttar Pradesh, India. Vasu Gupta, MBBS, is affiliated with Dayanand Medical College and Hospital, Ludhiana, India. Ridhimaa Jain, MBBS, MD, is a specialist pediatrician, Centre of Excellence–Early Intervention Centre, Department of Paediatrics, Lok Nayak Hospital and Maulana Azad Medical College, New Delhi, India. Rohit Jain, MD, is assistant professor of medicine at Penn State Health Milton S. Hershey Medical Center. The authors and planner for this educational activity have no relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing health care products used by or on patients.
Process
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Expiration date:
Credit eligibility for this article is set to expire on May 1, 2025.
Target Audience
All physicians
Learning Objectives
After completing the article, the learner should be able to:
- Describe the modes of transmission of the monkeypox virus.
- Identify the pathogenesis and presenting clinical features of monkeypox.
- Recognize similarities and differences between monkeypox and smallpox viral infection.
- Prinay Sohal - Dayanand Medical College and Hospital, Ludhiana, India
- Aakanksha Gupta - Dayanand Medical College and Hospital, Ludhiana, India
- Shefali Gupta, MD - Department of Microbiology, All India Institute of Medical Sciences, AIIMS Raebareli, Uttar Pradesh
- Vasu Gupta, MBBS - Dayanand Medical College and Hospital, Ludhiana, India
- Ridhimaa Jain, MD - Department of Pediatrics, Centre of Excellence-Early Intervention Centre, Lok Nayak Hospital and Maulana Azad Medical College, New Delhi
- Rohit Jain, MD - Department of Medicine, Penn State Health Milton S. Hershey Medical Centre, Hershey, Pennsylvania
Corresponding author:
- Aakanksha Gupta - Dayanand Medical College, India (e-mail: aakanshaguptabti@gmail.com)
Accreditation
The A. Webb Roberts Center for Continuing Medical Education of Baylor Scott & White Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation
AMA PRA Category 1 Credit™
The A. Webb Roberts Center for Continuing Medical Education of Baylor Scott & White Health designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
American Board of Internal Medicine Maintenance of Certification (MOC)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1 MOC point in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Available Credit
- 1.00 American Board of Internal Medicine (ABIM) MOC Part 2Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
- 1.00 AMA PRA Category 1 Credit™The A. Webb Roberts Center for Continuing Medical Education of Baylor Scott & White Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
- 1.00 Attendance