We present the case of a 46-year-old man with bilateral renal artery stenosis and a previous stent placed on the left renal artery who presented with a hypertensive emergency with flash pulmonary edema, and acute-on-chronic renal failure. A renal angiogram revealed extensive thrombosis and in-stent restenosis, which were treated with thrombectomy, angioplasty, and stenting. Our case highlights the importance of careful patient selection for renal artery stenting and close monitoring poststenting due to the risk of serious complications.