2025 Clinician Corner - Aceruloplasminemia as a rare hereditary disease: four case reports in a single center
Aceruloplasminemia, which is a very rare iron metabolism disorder, may present with extremely nonspecific complaints, and disease screening should be considered, especially in patients with consanguineous marriages. We share four cases diagnosed with aceruloplasminemia and their characteristics. The first three cases were related to each other and have consanguineous marriages in their family history. Our first and fourth cases were diagnosed with aceruloplasminemia upon detecting hypochromic microcytic anemia, low transferrin saturation, and a high ferritin level in the examinations performed after a nonspecific complaint such as fatigue. Even though the second and third cases had no complaints, they were diagnosed during screening tests because they were relatives of the first case.
2025 Clinician Corner - Amaurosis fugax in Takayasu arteritis mimicking migraine with visual aura
Takayasu arteritis is a rare vasculitis commonly seen in young women. Amaurosis fugax and headache are visual presentations of Takayasu arteritis. Migraine with visual aura is a common condition affecting young women, and differentiating migraine from Takayasu presenting with visual symptoms and headache can be challenging. We present a case of a young woman initially misdiagnosed with migraine with aura, who was later found to have Amaurosis fugax as an early manifestation of Takayasu arteritis.
2025 Clinician Corner - Urrets-Zavalia syndrome and secondary acute angle-closure glaucoma induced by implantable collamer lens
Implantable collamer lenses (ICL) have revolutionized the management of high refractive errors, yet they present unique challenges. We present a case of a fixed and dilated atonic pupil following acute-angle closure glaucoma from pupillary block after ICL implantation, known as Urrets-Zavalia syndrome. A 39-year-old woman developed acute ocular pain and headaches after surgery, leading to elevated intraocular pressure and subsequent complications necessitating ICL removal. This case highlights the need for prompt identification and management of elevated intraocular pressure to prevent irreversible complications such as Urrets-Zavalia syndrome following ICL implantation.
2025 Clinician Corner - Histologic changes of basal cell carcinomas during vismodegib treatment
We report a case of a 63-year-old man with a history of numerous basal cell carcinomas (BCCs) on vismodegib who developed a pink subcutaneous nodule that was thought to be either a BCC or an epidermal inclusion cyst. Sections displayed a dome-shaped lesion composed of large dermal nodules of epithelioid cells with variable cytology. Some of the dermal nodules demonstrated squamatization of the epithelioid cells while others had a predominantly basaloid phenotype. Central necrosis was present in the majority of the large dermal nodules, but the lesion did not stain with CK7 or CK20, helping to rule out internal metastases. The epithelial nodules stained strongly with pancytokeratin (AE1/AE3), p40, and stained lightly with BCL-2, supporting the diagnosis of BCC. However, Ber-EP4 being negative and the presence of significant squamatization suggest vismodegib can alter both the histological and immunophenotype of BCCs. This phenomenon has rarely been reported in literature. 
2025 Accelerate Module I - Hospitalists/Inpatient-20250326

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2025 Quality Alliance Lunch and Learn: Supportive Palliative Care - Non-Traditional Pain Management - 20250228

Lunch & Learn will enhance providers competency in evidence-based pain management by equipping them with practical skills for assessing, diagnosing, and managing both acute and chronic pain conditions.

Mark Casanova, MD

Art of Communication-20250625 (Dallas) for HTPN Leadership

THIS COURSE HAS BEEN DEVELOPED FOR BAYLOR SCOTT & WHITE EMPLOYEES AND AFFILIATES ONLY. 
Outside participation is not available for the Art of Communication courses at this time.

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Art of Communication-20250430 (College Station)

THIS COURSE HAS BEEN DEVELOPED FOR BAYLOR SCOTT & WHITE EMPLOYEES AND AFFILIATES ONLY. 
Outside participation is not available for the Art of Communication courses at this time.

Please click the "Register Tab" above to register for this session.

Art of Communication-20250318 (College Station)

THIS COURSE HAS BEEN DEVELOPED FOR BAYLOR SCOTT & WHITE EMPLOYEES AND AFFILIATES ONLY. 
Outside participation is not available for the Art of Communication courses at this time.

Please click the "Register Tab" above to register for this session.

2025 Accelerate Module I - Hospitalists/Inpatient-20250213

Please click "Begin" to evaluate and claim credit.

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